1,2,4-Triazole

• CAT Number: R015708
• CAS Number: 288-88-0
• Molecular Formula: C2H3N3
• Molecular Weight: 69.067
• Purity: ≥95%
• Synonyms: 1H-1,2,4-Triazole; s-Triazole; 3,4-Diazapyrrole; 4H-1,2,4-Triazole; NSC 8312
• Storage: -20°C
• IUPAC Name: 1H-1,2,4-triazole
• InChI: InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)
• InChIKey: NSPMIYGKQJPBQR-UHFFFAOYSA-N
• SMILES: C1=NC=NN1

1,2,4-Triazole (CAS 288-88-0) and its derivatives are important structural moieties of many pharmaceutical drugs. Triazoles form coordination complexes with transition metal ions as ligands.Due to their electron-deficient nature, they exhibit excellent electron-transport and hole-blocking properties, making them promising organic materials in material science applications.

Reference

1.Al-Masoudi, I. A., et al. "1, 2, 4-Triazoles: Synthetic approaches and pharmacological importance." Chemistry of Heterocyclic Compounds 42.11 (2006): 1377-1403.
2.Haasnoot, Jaap G. "Mononuclear, oligonuclear and polynuclear metal coordination compounds with 1, 2, 4-triazole derivatives as ligands." Coordination Chemistry Reviews 200 (2000): 131-185.
3.Diaz-Ortiz, Angel, et al. "Applications of metal-free 1, 2, 4-triazole derivatives in materials science." Current Organic Chemistry 19.7 (2015): 568-584.