For research use only. Not for therapeutic Use.
Fluprostenol isopropyl ester (Item No. <span class=/itemid/>16769</span>) is a potent F-<wbr></wbr>series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. 13,14-<wbr></wbr>epoxy Fluprostenol isopropyl ester (Item No. <span class=/itemid/>13679</span>) is an impurity generated in the production of fluprostenol isopropyl ester. This product is a chiral enantiomer of the epoxide. The pharmacology of 13(S),14(S)-<wbr></wbr>epoxy fluprostenol isopropyl ester has not been studied extensively to date.
| Catalog Number | R054645 |
| Synonyms | Epoxy Derivative 2;13(S),14(S)-epoxy Travoprost |
| Molecular Formula | C26H35F3O7 |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C26H35F3O7/c1-15(2)35-22(33)11-6-4-3-5-10-18-19(30)13-20(31)23(18)25-24(36-25)21(32)14-34-17-9-7-8-16(12-17)26(27,28)29/h3,5,7-9,12,15,18-21,23-25,30-32H,4,6,10-11,13-14H2,1-2H3/b5-3-/t18-,19-,20+,21-,23+,24-,25-/m0/s1 |
| InChIKey | BGPCWSPTSAFVAF-MBCUBKMDSA-N |
| SMILES | O[C@@H]1[C@H](C/C=CCCCC(OC(C)C)=O)[C@@H]([C@@H]2C([C@@H](O)COC3=CC=CC(C(F)(F)F)=C3)O2)[C@H](O)C1 |
| Reference | 1.Sorbera, L.A., and Castañer, J. Travoprost. Drugs of the Future 25, 41-45 (2000). |
