1,4-Bis(benzhydryl)piperazine

• CAT Number: C000583
• CAS Number: 216581-01-0
• Molecular Formula: C₃₀H₃₀N₂
• Molecular Weight: 418.57
• Purity: ≥95%
• Synonyms: 1,4-Bis(diphenylmethyl)piperazine; 1,4-Bisbenzhydrylpiperazine; Cinnarizine EP Impurity E
• Solubility: Chloroform (Slightly), DMSO (Slightly, Heated)
• Appearance: White to Off-White Solid
• Storage: 4°C, Inert atmosphere, Light sensitive

1,4-Bis(benzhydryl)piperazine(CAT: C000583) is a compound that serves as an impurity associated with Cinnarizine, a medication used to treat conditions like motion sickness and vertigo. In pharmaceutical chemistry, monitoring and controlling impurities like 1,4-Bis(benzhydryl)piperazine in Cinnarizine is crucial for ensuring the purity and safety of the drug product.

Reference

Zhang, H., et al.: Biochemistry, 43, 8290 (2004); Pandey, A., et al.: J. Pharm. Biomed. Anal., 20, 203 (1999); Andrews, S., et al.: J. Med. Chem., 53, 916 (2010);