1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE

• CAT Number: M134721
• CAS Number: 100991-92-2
• Molecular Formula: C5H11NO3 • HCl
• Molecular Weight: 169.6
• Purity: ≥95%
• Synonyms: DAB
• Storage: -20°C
• InChIKey: PZGVJCJRMKIVLJ-DEVUXVJFSA-N

1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 µM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.