14,15-Dehydro Budesonide

• CAT Number: R051444
• CAS Number: 131918-64-4
• Molecular Formula: C₂₅H₃₂O₆
• Molecular Weight: 428.52
• Purity: ≥95%
• Synonyms: (11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4,14-triene-3,20-dione; Budesonide Impurity E (EP)
• Storage: -20°C
• IUPAC Name: (1R,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-2,14,17-trien-16-one
• InChI: InChI=1S/C25H32O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-11,16,18,20-22,26,28H,4-7,12-13H2,1-3H3/t16-,18-,20+,21?,22+,23-,24-,25+/m0/s1
• InChIKey: PMZXYZGZQZYDLA-BQKXZEBKSA-N
• SMILES: CCCC1OC2C=C3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C

14,15-Dehydro Budesonide (Cat No.:R051444) is a synthetic compound derived from budesonide, which is a glucocorticoid steroid used as an anti-inflammatory agent, particularly in the treatment of various respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). The “14,15-dihydro” modification refers to the removal of hydrogen atoms at positions 14 and 15 on the steroid molecule. This modification can influence the compound’s pharmacological activity and metabolic properties. Such modifications are often performed to study the structure-activity relationships of steroid compounds and their potential therapeutic applications.