(14R)-14-Hydroxyclarithromycin

• CAT Number: R068066
• CAS Number: 116836-41-0
• Molecular Formula: C38H69NO14
• Molecular Weight: 763.95
• Purity: ≥95%
• Synonyms: clarithromycin
• Storage: RT
• IUPAC Name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
• InChI: InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
• InChIKey: AGOYDEPGAOXOCK-KCBOHYOISA-N
• SMILES: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)O)(C)O

(14R)-14-Hydroxyclarithromycin(CAT: R068066) is a metabolite of the macrolide antibiotic Clarithromycin, known for its enhanced antibacterial activity against a broad spectrum of pathogens. This compound retains the antimicrobial properties of its parent drug while exhibiting increased potency, particularly against certain resistant strains of bacteria. (14R)-14-Hydroxyclarithromycin is essential in pharmaceutical research for studying the pharmacokinetics, metabolism, and efficacy of Clarithromycin and its derivatives. Its role in understanding the drug’s metabolic pathways and optimizing antibiotic therapy makes it a valuable tool for researchers focused on infectious diseases, antibiotic resistance, and the development of novel antibacterial agents.