For research use only. Not for therapeutic Use.
15-<wbr></wbr><em>epi</em> PGA<sub>1</sub> is the 15(R) stereoisomer of PGA<sub>1</sub>. Prostaglandins of the A-<wbr></wbr>series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA<sub>1</sub> causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive patients. There are no published reports on the biological activity of 15-<wbr></wbr><em>epi</em> PGA<sub>1</sub> at this time.
Catalog Number | R042469 |
CAS Number | 20897-92-1 |
Synonyms | 15-epi PGA1 |
Molecular Formula | C20H32O4 |
Purity | ≥95% |
Storage | -20°C |
InChI | InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/b14-12+/t16-,17+,18+/m0/s1 |
InChIKey | BGKHCLZFGPIKKU-AHUSATQRSA-N |
SMILES | CCCCC[C@@H](O)/C=C/[C@H]([C@H]1CCCCCCC(O)=O)C=CC1=O |
Reference | 1.Krakoff, L.R.,Vlachakis, N.,Mendlowitz, M., et al. Differential effect of prostaglandin A1 in hypertensive patients with low, normal and high renin. Clinical Science and Molecular Medicine 48, 311s-313s (1975). |