15-Keto Bimatoprost

• CAT Number: R057190
• CAS Number: 1163135-96-3
• Molecular Formula: C25H35NO4
• Molecular Weight: 413.55
• Purity: ≥95%
• Synonyms: (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
• InChI: InChI=1S/C25H35NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,21-24,28-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t21-,22-,23+,24-/m1/s1
• InChIKey: OZCBJWOYRKMMPF-QWPROEHNSA-N
• SMILES: CCNC(=O)CCCC=CCC1C(CC(C1C=CC(=O)CCC2=CC=CC=C2)O)O

15-Keto Bimatoprost (Cat No.: R057190) is a metabolite of Bimatoprost, a prostaglandin analog widely used in glaucoma and ocular hypertension treatment. It plays a role in regulating intraocular pressure (IOP) by enhancing aqueous humor outflow. With its modified 15-keto structure, it is useful for metabolic and pharmacokinetic studies, aiding in understanding prostaglandin analog metabolism and receptor interactions. Ideal for ophthalmic drug research, 15-Keto Bimatoprost supports the development of novel ocular therapies and precision medicine approaches in eye disease management.

Reference

[1]. Rahman MS, et al. Screening and quantification of undeclared PGF2α analogs in eyelash-enhancing cosmetic serums using LC-MS/MS. J Pharm Biomed Anal. 2022 Sep 20;219:114940.
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