For research use only. Not for therapeutic Use.
13,14-<wbr></wbr>dihydro-<wbr></wbr>15-<wbr></wbr>keto Prostaglandin E<sub>1</sub> (PGE<sub>1</sub>) is a metabolite of PGE<sub>1</sub> with much reduced biological activity. Steady state plasma concentrations are about 10 pg/ml. 13,14-<wbr></wbr>dihydro-<wbr></wbr>15-<wbr></wbr>keto PGE<sub>1</sub> is a weak inhibitor of ADP-<wbr></wbr>induced platelet aggregation in human PRP and washed platelets with IC<sub>50</sub> values of 54 and 200 µM, respectively, compared to PGE<sub>1</sub> which has an IC<sub>50</sub> of 40 nM.
| Catalog Number | R063955 |
| CAS Number | 5094-14-4 |
| Synonyms | (11α)-11-Hydroxy-9,15-dioxo-prostan-1-oic Acid; 3-Hydroxy-5-oxo-2-(3-oxooctyl)-cyclopentaneheptanoic Acid; 3-Hydroxy-5-oxo-2-(3-oxooctyl)-cyclopentaneheptanoic Acid Stereoisomer; 11α-Hydroxy-9,15-diketoprostanoic Acid; 11α-Hydroxy-9,15-dioxoprostanoi |
| Molecular Formula | C20H34O5 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 7-[(1R,2R,3R)-3-hydroxy-5-oxo-2-(3-oxooctyl)cyclopentyl]heptanoic acid |
| InChI | InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h16-17,19,23H,2-14H2,1H3,(H,24,25)/t16-,17-,19-/m1/s1 |
| InChIKey | CDUVSQMTLOYKTR-ZHALLVOQSA-N |
| SMILES | CCCCCC(=O)CCC1C(CC(=O)C1CCCCCCC(=O)O)O |
