15-Lipoxygenase Inhibitor 1

• CAT Number: R039495
• CAS Number: 928853-86-5
• Molecular Formula: C16H19N5S
• Molecular Weight: 313.42
• Purity: ≥95%
• Synonyms: 15-LO Inhibitor 1
• Target: Apoptosis
• Storage: -20°C
• IUPAC Name: 4-methyl-2-(4-methylpiperazin-1-yl)-5H-pyrimido[4,5-b][1,4]benzothiazine
• InChI: InChI=1S/C16H19N5S/c1-11-14-15(22-13-6-4-3-5-12(13)18-14)19-16(17-11)21-9-7-20(2)8-10-21/h3-6,18H,7-10H2,1-2H3
• InChIKey: HYPHGMNLWIKEMB-UHFFFAOYSA-N
• SMILES: CC1=C2C(=NC(=N1)N3CCN(CC3)C)SC4=CC=CC=C4N2

15-Lipoxygenase Inhibitor 1（Cat No.:R039495）is a selective inhibitor targeting the 15-lipoxygenase enzyme, which plays a key role in lipid metabolism and inflammatory processes by converting arachidonic acid into pro-inflammatory mediators. This inhibitor is studied for its potential in reducing inflammation and oxidative stress, making it valuable in researching treatments for conditions such as asthma, atherosclerosis, and certain cancers. By preventing the formation of leukotrienes and other inflammatory compounds, 15-Lipoxygenase Inhibitor 1 helps elucidate pathways of immune response, offering a targeted approach to manage inflammatory and oxidative stress-related diseases.

Reference

1.Gaffney, B.J. Lipoxygenases: Structural principles and spectroscopy. Annual Reviews of Biophysical and Biomolecular Structure 25, 431-459 (1996).