15(S)-HEPE

• CAT Number: R067232
• CAS Number: 86282-92-0
• Molecular Formula: C20H30O3
• Molecular Weight: 318.46
• Purity: ≥95%
• Synonyms: 15S-hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acid; (5Z,8Z,11Z,13E,15S,17Z)-15-hydroxyicosa-5,8,11,13,17-pentaenoic acid
• Storage: -20°C
• IUPAC Name: (5Z,8Z,11Z,13E,15S,17Z)-15-hydroxyicosa-5,8,11,13,17-pentaenoic acid
• InChI: InChI=1S/C20H30O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h3-5,8-11,13-14,17,19,21H,2,6-7,12,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,13-3-,17-14+/t19-/m0/s1
• InChIKey: WLKCSMCLEKGITB-DBVSHIMFSA-N
• SMILES: CCC=CCC(C=CC=CCC=CCC=CCCCC(=O)O)O

15(S)-HEPE (15(S)-Hydroxyeicosapentaenoic Acid)(CAT: R067232 is a bioactive lipid derived from the omega-3 fatty acid eicosapentaenoic acid (EPA). It is produced through the action of 15-lipoxygenase, an enzyme that catalyzes the oxygenation of EPA, leading to the formation of 15(S)-HEPE. This compound is of significant interest in inflammation research due to its role as a mediator in the resolution of inflammation. 15(S)-HEPE exerts anti-inflammatory effects by modulating immune cell function and reducing the production of pro-inflammatory cytokines. It is also involved in the regulation of lipid metabolism and has been studied for its potential benefits in conditions like cardiovascular diseases, metabolic syndrome, and chronic inflammatory disorders. As a part of the broader family of specialized pro-resolving mediators (SPMs), 15(S)-HEPE is important for understanding the pathways that control inflammation and tissue homeostasis.