15(S)-HETE Lipid Maps® MS Standard

• CAT Number: R015748
• CAS Number: 54845-95-3
• Molecular Formula: C20H32O3
• Molecular Weight: 320.473
• Purity: ≥95%
• Synonyms: 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid
• Target: Endogenous Metabolite
• Storage: -20°C
• IUPAC Name: (5Z,8Z,11Z,13E,15S)-15-hydroxyicosa-5,8,11,13-tetraenoic acid
• InChI: InChI=1S/C20H32O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h4-5,8-11,14,17,19,21H,2-3,6-7,12-13,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,17-14+/t19-/m0/s1
• InChIKey: JSFATNQSLKRBCI-VAEKSGALSA-N
• SMILES: CCCCCC(C=CC=CCC=CCC=CCCCC(=O)O)O

15(S)-<wbr></wbr>HETE is a major arachidonic acid metabolite from the 15-<wbr></wbr>lipoxygenase pathway. In mammals, 15(S)-<wbr></wbr>HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes. 15(S)-<wbr></wbr>HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.

Reference

1.Nadel, J.A.,Conrad, D.J.,Ueki, I.F., et al. Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocyes, leukocytes, and airway cells. Journal of Clinical Investigation 87, 1139-1145 (1991).