(15R)-Bimatoprost

For research use only. Not for therapeutic Use.

  • CAT Number: R050503
  • CAS Number: 1163135-92-9
  • Molecular Formula: C25H37NO4
  • Molecular Weight: 415.57
  • Purity: ≥95%
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(15R)-Bimatoprost(Cat No.: R050503) is a stereoisomer of bimatoprost, a synthetic prostaglandin analog used primarily to treat glaucoma and ocular hypertension. It works by increasing the outflow of aqueous humor from the eye, thereby reducing intraocular pressure. The (15R) form may possess specific pharmacological properties that could improve efficacy, selectivity, or reduce side effects compared to other forms of bimatoprost. Research into (15R)-bimatoprost focuses on optimizing its therapeutic potential for managing eye conditions like glaucoma while exploring its broader applications in ocular health.


CAS Number 1163135-92-9
Synonyms

(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide

Molecular Formula C25H37NO4
Purity ≥95%
InChI InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21-,22-,23+,24-/m1/s1
InChIKey AQOKCDNYWBIDND-ZPFRTTICSA-N
SMILES CCNC(=O)CCCC=CCC1C(CC(C1C=CC(CCC2=CC=CC=C2)O)O)O
Reference

[1]. Dams I, et al. A novel convergent synthesis of the antiglaucoma PGF2α analogue bimatoprost. Chirality. 2013 Mar;25(3):170-9.
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