16α-Methyl Prednisolone

• CAT Number: R058912
• CAS Number: 10417-63-7
• Molecular Formula: C22H30O5
• Molecular Weight: 374.48
• Purity: ≥95%
• Synonyms: (11β,16α)-11,17,21-Trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 11β,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione; 16α-Methylprednisolone
• Storage: Room temperature
• IUPAC Name: (8S,9S,10R,11S,13S,14S,16R,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
• InChI: InChI=1S/C22H30O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-20(13,2)19(15)17(25)10-21(16,3)22(12,27)18(26)11-23/h6-7,9,12,15-17,19,23,25,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19-,20+,21+,22+/m1/s1
• InChIKey: WNYLPFCKNQAAMB-PPUNREKOSA-N
• SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3C(CC2(C1(C(=O)CO)O)C)O)C

16α-Methyl prednisolone (Cat No.: R058912) is a synthetic glucocorticoid derived from prednisolone. It exhibits anti-inflammatory and immunosuppressive properties similar to other corticosteroids. This compound is used to treat various inflammatory conditions, allergies, and autoimmune disorders. Its chemical modification at the 16α position enhances its potency and duration of action compared to prednisolone. Like other glucocorticoids, it works by binding to glucocorticoid receptors, modulating gene expression, and suppressing inflammatory responses in the body.