For research use only. Not for therapeutic Use.
16-Azidohexadecanoic acid, a synthetic fatty acid, can be used as a modification marker for nucleotides and a molecular probe for fatty acid metabolism[1][2]. 16-Azidohexadecanoic acid is a click chemistry reagent, itcontains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Catalog Number | I043389 |
CAS Number | 112668-54-9 |
Synonyms | 16-azidohexadecanoic acid |
Molecular Formula | C16H31N3O2 |
Purity | ≥95% |
InChI | InChI=1S/C16H31N3O2/c17-19-18-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16(20)21/h1-15H2,(H,20,21) |
InChIKey | VLFHDUVVGCRNIZ-UHFFFAOYSA-N |
SMILES | C(CCCCCCCC(=O)O)CCCCCCCN=[N+]=[N-] |
Reference | [1]. J Balintová,et al. Antibody-nucleotide conjugate as a substrate for DNA polymerases. Chem Sci. 2018 Jul 24;9(35):7122-7125. [2]. Alexander J Pérez, et al. ω-Azido fatty acids as probes to detect fatty acid biosynthesis, degradation, and modification. J Lipid Res. 2014 Sep;55(9):1897-901. |