1,6-Naphthalenedisulfonic acid disodium salt

• CAT Number: M123975
• CAS Number: 1655-43-2
• Molecular Formula: C10H6Na2O6S2
• Molecular Weight: 332.252
• Purity: ≥95%
• Synonyms: Sodium naphthalene-1,6-disulfonate; 1,6-Naphthalenedisulfonic Acid Disodium Salt; Disodium 1,6-Naphthalenedisulfonate; 1,6-Naphthalenedisulfonic acid, disodium salt
• Storage: -20°C
• IUPAC Name: disodium;naphthalene-1,6-disulfonate
• InChI: InChI=1S/C10H8O6S2.2Na/c11-17(12,13)8-4-5-9-7(6-8)2-1-3-10(9)18(14,15)16;;/h1-6H,(H,11,12,13)(H,14,15,16);;/q;2*+1/p-2
• InChIKey: FXJFYEOXUWERCL-UHFFFAOYSA-L
• SMILES: C1=CC2=C(C=CC(=C2)S(=O)(=O)[O-])C(=C1)S(=O)(=O)[O-].[Na+].[Na+]

1,6-Naphthalenedisulfonic acid disodium salt (CAS 1655-43-2) is off white powder, which can be used as a dye intermediate. It was used to synthesize a novel Ca(II) coordination polymer.

Reference

1. Materials (Basel). 2013 Aug 16;6(8):3547-3555. doi: 10.3390/ma6083547.Synthesis, Structural Characterization, and Antitumor Activity of a Ca(II) Coordination Polymer Based on 1,6-Naphthalenedisulfonate and 4,4'-Bipyridyl.Tai X(1), Zhao W(2).

 

A novel Ca(II) coordination polymer, [CaL(4,4'-bipyridyl)(H₂O)₄]n (L = 1,6-naphthalenedisulfonate), was synthesized by reaction of calcium perchlorate with 1,6-naphthalenedisulfonic acid disodium salt and 4,4'-bipyridyl in CH₃CH₂OH/H₂O. It was characterized by elemental analysis, IR, molar conductivity and thermogravimetric analysis. X-ray crystallography reveals that the Ca(II) coordination polymer belongs to the orthorhombic system, with space group P2₁2₁2₁. The geometry of the Ca(II) ion is a distorted CaNO₆ pengonal bipyramid, arising from its coordination by four water molecules, one nitrogen atom of 4,4'-bipyridyl molecule, and two oxygen atoms from two L ligands. The complex molecules form a helical chain by self-assembly. The antitumor activity of 1,6-naphthalenedisulfonic acid disodium salt and the Ca(II) coordination polymer against human hepatoma smmc-7721 cell line and human lung adenocarcinoma A549 cell line reveals that the Ca(II) coordination polymer inhibits cell growth of human lung adenocarcinoma A549 cell line with IC50 value of 27 μg/mL, and is more resistive to human lung adenocarcinoma A549 cell line as compared to 1,6-naphthalenedisulfonic acid disodium salt.