16-(S)-Iloprost-d4

• CAT Number: R015542
• CAS Number: NA
• Molecular Formula: C₂₂H₂₈D₄O₄
• Molecular Weight: 364.51
• Purity: ≥95%
• Synonyms: 5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S,4S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]pentanoic Acid-d4
• Storage: -20°C
• IUPAC Name: (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]-3,3,4,4-tetradeuteriopentanoic acid
• InChI: InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15-,17-,18+,19-,20+,21+/m0/s1/i5D2,6D2
• InChIKey: HIFJCPQKFCZDDL-GHNZVGHFSA-N
• SMILES: [2H]C([2H])(CC(=O)O)C([2H])([2H])/C=C/1\C[C@H]2C[C@H]([C@@H]([C@H]2C1)/C=C/[C@H]([C@@H](C)CC#CC)O)O

16-(S)-Iloprost-d4 is a deuterium-labeled analogue of 16-(S)-Iloprost, a synthetic prostacyclin analogue. It acts by binding to prostacyclin receptors, leading to vasodilation and inhibition of platelet aggregation. In pharmaceutical chemistry, it is used for studying pulmonary arterial hypertension and peripheral vascular diseases, providing insights into drug action and metabolism. The deuterium labeling aids in precise mass spectrometry analysis, facilitating pharmacokinetic and metabolic studies. Researchers utilize it to explore drug interactions and stability, ensuring the efficacy and safety of therapeutic formulations in clinical applications.