17α-Des-(2-hydroxyacetyl)budesonide 17α-Carboxylic Acid

• CAT Number: R045826
• CAS Number: 192057-49-1
• Molecular Formula: C24H32O6
• Molecular Weight: 416.514
• Purity: ≥95%
• Synonyms: (11β,16α,17α)-16,17-[Butylidenebis(oxy)]-11-hydroxy-3-oxo-androsta-1,4-diene-17-carboxylic Acid; 17-Carboxy Budesonide.
• Storage: Room temperature
• IUPAC Name: 11-hydroxy-9,13-dimethyl-16-oxo-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-diene-8-carboxylic acid
• InChI: InChI=1S/C24H32O6/c1-4-5-19-29-18-11-16-15-7-6-13-10-14(25)8-9-22(13,2)20(15)17(26)12-23(16,3)24(18,30-19)21(27)28/h8-10,15-20,26H,4-7,11-12H2,1-3H3,(H,27,28)/t15-,16-,17-,18+,19?,20+,22-,23-,24-/m0/s1
• InChIKey: GHPORMLBYXHFAV-SREVKRBTSA-N
• SMILES: CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)O)C)O)C

17α-Des-(2-hydroxyacetyl)budesonide 17α-Carboxylic Acid is a derivative of budesonide, a potent corticosteroid used in treating inflammatory conditions. This compound features a carboxylic acid group that enhances its pharmacological properties. It is studied for its potential in improving therapeutic efficacy while reducing side effects associated with conventional corticosteroids. Its unique structural modifications may lead to enhanced bioavailability and targeted delivery in clinical applications. Research into this compound contributes to the ongoing development of safer and more effective anti-inflammatory therapies.