(19E/Z)-seco-[4-O-[2-Hydroxy(ethyl)-d4]] Rapamycin Sodium Salt

• CAT Number: R052412
• CAS Number: NA
• Molecular Formula: C₅₃H₇₈D₄NNaO₁₄
• Molecular Weight: 984.23
• Purity: ≥95%
• Synonyms: (2S)-1-[2-oxo-2-[(2R,3R,6S)-tetrahydro-2-hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19Z,21R)-14-hydroxy-22-[(1S,3R,4R)-4-[2-hydroxy(ethoxy)-d4]-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaen-1
• Storage: -80°C

(19E/Z)-seco-[4-O-[2-Hydroxy(ethyl)-d4]] Rapamycin Sodium Salt is a deuterated derivative of rapamycin, a potent immunosuppressant and anticancer agent. In this compound, the ethyl group attached to the 4-O position of rapamycin is modified by replacing four hydrogen atoms with deuterium (d4). This deuteration enhances the stability of the molecule and aids in tracking its pharmacokinetics and metabolism in research studies, particularly using mass spectrometry. The sodium salt form improves the compound’s solubility and stability, making it suitable for use in various experimental settings, especially those involving the study of rapamycin’s mechanisms and interactions.