(1R,2S)-Xeruborbactam disodium

• CAT Number: I043465
• CAS Number: 2170836-14-1
• Molecular Formula: C10H8BFNa2O5
• Molecular Weight: 283.96
• Purity: ≥95%
• Synonyms: disodium;(2R,4S)-9-fluoro-5,5-dihydroxy-6-oxa-5-boranuidatricyclo[5.4.0.02,4]undeca-1(7),8,10-triene-8-carboxylate
• InChI: InChI=1S/C10H9BFO5.2Na/c12-7-2-1-4-5-3-6(5)11(15,16)17-9(4)8(7)10(13)14;;/h1-2,5-6,15-16H,3H2,(H,13,14);;/q-1;2*+1/p-1/t5-,6-;;/m0../s1
• InChIKey: RLVWXGRGTAHSCI-USPAICOZSA-M
• SMILES: [B-]1([C@H]2C[C@H]2C3=C(O1)C(=C(C=C3)F)C(=O)[O-])(O)O.[Na+].[Na+]

(1R,2S)-Xeruborbactam disodium（Cat No.:I043465）is a novel β-lactamase inhibitor designed to combat antibiotic-resistant bacterial infections. It is a stereoisomer with specific configurations at the 1R and 2S positions, which influence its binding affinity and efficacy in inhibiting β-lactamase enzymes. These enzymes typically degrade β-lactam antibiotics, rendering them ineffective. By inhibiting β-lactamase activity, (1R,2S)-Xeruborbactam disodium enhances the potency of β-lactam antibiotics, restoring their effectiveness against resistant pathogens. It is being explored in combination therapies to treat multidrug-resistant bacterial infections, including those caused by Gram-negative bacteria.