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(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid 1-Methylethyl Ester
For research use only. Not for therapeutic Use.
(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid 1-Methylethyl Ester(CAT: C000639) plays a significant role in the context of pharmaceuticals, particularly related to urinary incontinence treatment. It is identified as an impurity present in Solifenacin, a muscarinic M3 receptor antagonist utilized for managing urinary incontinence. Monitoring and understanding the presence of this impurity in Solifenacin formulations is crucial for ensuring the quality and safety of the medication.
Catalog Number | C000639 |
CAS Number | 1353274-25-5 |
Synonyms | Solifenacin Impurity B; (S)-Isopropyl 1-Phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate; |
Molecular Formula | C₁₉H₂₁NO₂ |
Purity | ≥95% |
Solubility | Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Sl |
Appearance | Colourless Oil to Thick Oil |
Storage | 4°C |
Reference | Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006), |