(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid 1-Methylethyl Ester

For research use only. Not for therapeutic Use.

  • CAT Number: C000639
  • CAS Number: 1353274-25-5
  • Molecular Formula: C₁₉H₂₁NO₂
  • Molecular Weight: 295.38
  • Purity: ≥95%
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(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid 1-Methylethyl Ester(CAT: C000639) plays a significant role in the context of pharmaceuticals, particularly related to urinary incontinence treatment. It is identified as an impurity present in Solifenacin, a muscarinic M3 receptor antagonist utilized for managing urinary incontinence. Monitoring and understanding the presence of this impurity in Solifenacin formulations is crucial for ensuring the quality and safety of the medication.


Catalog Number C000639
CAS Number 1353274-25-5
Synonyms

Solifenacin Impurity B; (S)-Isopropyl 1-Phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate;

Molecular Formula C₁₉H₂₁NO₂
Purity ≥95%
Solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Sl
Appearance Colourless Oil to Thick Oil
Storage 4°C
Reference

Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006),

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