(1S)-Perindopril-d4 Benzyl Ester

• CAT Number: R007254
• CAS Number: NA
• Molecular Formula: C₂₆H₃₄D₄N₂O₅
• Molecular Weight: 462.61
• Purity: ≥95%
• Synonyms: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic Acid Benzyl Ester-d4
• Storage: -20°C
• IUPAC Name: benzyl (2S,3aS,7aS)-1-[(2S)-2,3,3,3-tetradeuterio-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylate
• InChI: InChI=1S/C26H38N2O5/c1-4-11-21(25(30)32-5-2)27-18(3)24(29)28-22-15-10-9-14-20(22)16-23(28)26(31)33-17-19-12-7-6-8-13-19/h6-8,12-13,18,20-23,27H,4-5,9-11,14-17H2,1-3H3/t18-,20-,21-,22-,23-/m0/s1/i3D3,18D
• InChIKey: ZNAYHAPFFQRGES-PTECYWEWSA-N
• SMILES: [2H][C@@](C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)OCC3=CC=CC=C3)(C([2H])([2H])[2H])N[C@@H](CCC)C(=O)OCC

(1S)-Perindopril-d4 Benzyl Ester is a deuterium-labeled derivative of Perindopril Benzyl Ester, a prodrug used in pharmaceutical chemistry. It functions by inhibiting angiotensin-converting enzyme (ACE), thereby lowering blood pressure and treating hypertension. This compound is crucial in pharmaceutical research, particularly in studying ACE inhibitors and their efficacy in cardiovascular treatments. Its deuterium-labeled form aids in pharmacokinetic studies, enhancing drug metabolism investigations and ensuring accurate quantification in biological samples for clinical trials and drug development processes.