2-(3-(Difluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

For research use only. Not for therapeutic Use.

  • CAT Number: L007230
  • CAS Number: 627525-89-7
  • Molecular Formula: C13H17BF2O2
  • Molecular Weight: 254.08
  • Purity: ≥95%
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2-(3-(Difluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(Cat No.:L007230), is a valuable chemical compound utilized in organic synthesis and medicinal chemistry research. Its structure incorporates a boron-containing dioxaborolane core substituted with a difluoromethylphenyl group. This compound is vital in Suzuki-Miyaura cross-coupling reactions, facilitating the creation of complex organic molecules. The trifluoromethyl group enhances the compound’s reactivity and properties, making it a significant tool in modern synthetic methodologies. Researchers utilize this compound as a key intermediate, enabling the design and synthesis of diverse bioactive molecules, contributing significantly to drug discovery efforts and advancements in the field of organic chemistry.


Catalog Number L007230
CAS Number 627525-89-7
Molecular Formula C13H17BF2O2
Purity ≥95%
Storage 2–8 °C
IUPAC Name 2-[3-(difluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
InChI InChI=1S/C13H17BF2O2/c1-12(2)13(3,4)18-14(17-12)10-7-5-6-9(8-10)11(15)16/h5-8,11H,1-4H3
InChIKey JELHVFORSVSSJD-UHFFFAOYSA-N
SMILES B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC=C2)C(F)F

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