2-(3-(Difluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

For research use only. Not for therapeutic Use.

  • CAT Number: L007230
  • CAS Number: 627525-89-7
  • Molecular Formula: C13H17BF2O2
  • Molecular Weight: 254.08
  • Purity: ≥95%
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2-(3-(Difluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(Cat No.:L007230), is a valuable chemical compound utilized in organic synthesis and medicinal chemistry research. Its structure incorporates a boron-containing dioxaborolane core substituted with a difluoromethylphenyl group. This compound is vital in Suzuki-Miyaura cross-coupling reactions, facilitating the creation of complex organic molecules. The trifluoromethyl group enhances the compound’s reactivity and properties, making it a significant tool in modern synthetic methodologies. Researchers utilize this compound as a key intermediate, enabling the design and synthesis of diverse bioactive molecules, contributing significantly to drug discovery efforts and advancements in the field of organic chemistry.


CAS Number 627525-89-7
Molecular Formula C13H17BF2O2
Purity ≥95%
Storage 2–8 °C
IUPAC Name 2-[3-(difluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
InChI InChI=1S/C13H17BF2O2/c1-12(2)13(3,4)18-14(17-12)10-7-5-6-9(8-10)11(15)16/h5-8,11H,1-4H3
InChIKey JELHVFORSVSSJD-UHFFFAOYSA-N
SMILES B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC=C2)C(F)F
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