2-[[[4-[(Z)-Amino[[(hexyloxy)carbonyl]imino]methyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid (>90%)

• CAT Number: C000034
• CAS Number: 1848337-06-3
• Molecular Formula: C₂₄H₂₉N₅O₄
• Molecular Weight: 451.52
• Purity: ≥95%
• Synonyms: Dabigatran Impurity
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
• Appearance: Off-White to Pale Beige Solid
• Storage: -20°C, Hygroscopic

2-[[[4-[(Z)-Amino[[(hexyloxy)carbonyl]imino]methyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid(CAT: C000034) is a compound of significance in pharmaceutical chemistry. It is recognized as a degradation product of Dabigatran, a nonpeptide, direct thrombin inhibitor used as an antithrombotic medication. Understanding the presence of degradation products like this compound is crucial for ensuring the stability and quality of drug formulations.

Reference

Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005)