2-Amino Adenosine

• CAT Number: R003119
• CAS Number: 2096-10-8
• Molecular Formula: C10H14N6O4
• Molecular Weight: 282.26
• Purity: ≥95%
• Synonyms: 2,6-Diamino-9-β-D-ribofuranosyl-9H-purine; 2,6-Diaminonebularine; 9-β-Ribosyl-2,6-diaminopurine; 2,6-Diaminopurine Riboside; 2,6-Diaminopurinosine; NSC 7363
• Target: Nucleoside Antimetabolite/Analog
• Storage: Store at -20°C
• IUPAC Name: (2R,3R,4S,5R)-2-(2,6-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• InChI: InChI=1S/C10H14N6O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H4,11,12,14,15)/t3-,5-,6-,9-/m1/s1
• InChIKey: ZDTFMPXQUSBYRL-UUOKFMHZSA-N
• SMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2N)N

2-Amino Adenosine (Cat.No:R003119) is a modified form of adenosine, a nucleoside found in RNA. The addition of an amino group makes it valuable in biochemical research. It is used to study adenosine receptor activity and has potential applications in drug development, particularly in the field of neurological disorders and cancer therapy.

Reference

1.Long, Mary C., Vincent Escuyer, and William B. Parker. "Identification and characterization of a unique adenosine kinase from Mycobacterium tuberculosis." Journal of bacteriology 185.22 (2003): 6548-6555.
2.Yadav, Vikas, et al. "Synthesis, Biological Activity and Molecular Modeling of 6-Benzylthioinosine Analogues as Subversive Substrates of Toxoplasma g ondii Adenosine Kinase." Journal of medicinal chemistry 47.8 (2004): 1987-1996.