2-Arachidonyl Glycerol-d5

• CAT Number: R052400
• CAS Number: 1215168-37-8
• Molecular Formula: C23H38O4
• Molecular Weight: 383.584
• Purity: ≥95%
• Synonyms: 5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid 2-Hydroxy-1-(hydroxymethyl)?ethyl-d5 Ester; (all-Z)-5,8,11,14-Eicosatetraenoic Acid 2-Hydroxy-1-?(hydroxymethyl)ethyl-d5 Ester; 2-Monoarachidonoylglycerol-d5
• Storage: -80°C
• IUPAC Name: (1,1,2,3,3-pentadeuterio-1,3-dihydroxypropan-2-yl) (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
• InChI: InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/i20D2,21D2,22D
• InChIKey: RCRCTBLIHCHWDZ-BGRPFJIQSA-N
• SMILES: [2H]C([2H])(C([2H])(C([2H])([2H])O)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)O

2-Arachidonyl Glycerol-d5 (2-AG-d5) is a deuterated analog of 2-arachidonyl glycerol, a naturally occurring endocannabinoid. It plays a crucial role in the endocannabinoid system by acting as a partial agonist at cannabinoid receptors CB1 and CB2, modulating various physiological processes such as pain, inflammation, and appetite. In research, 2-AG-d5 is used as a stable isotope-labeled internal standard in mass spectrometry-based quantification of endogenous 2-AG levels. Its applications are vital in pharmacological studies and metabolic profiling in pharmaceutical and biomedical research.