2-Chloro-4-nitrophenyl-α-D-glucopyranoside

• CAT Number: R000811
• CAS Number: 119047-14-2
• Molecular Formula: C12H14ClNO8
• Molecular Weight: 335.693
• Purity: ≥95%
• Synonyms: CNP-α-D-glucopyranoside
• Storage: -20°C
• IUPAC Name: (2R,3R,4S,5S,6R)-2-(2-chloro-4-nitrophenoxy)-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C12H14ClNO8/c13-6-3-5(14(19)20)1-2-7(6)21-12-11(18)10(17)9(16)8(4-15)22-12/h1-3,8-12,15-18H,4H2/t8-,9-,10+,11-,12+/m1/s1
• InChIKey: PJCVBKZRKNFZOD-ZIQFBCGOSA-N
• SMILES: C1=CC(=C(C=C1[N+](=O)[O-])Cl)OC2C(C(C(C(O2)CO)O)O)O

Carbohydrates conjugated with 2-<wbr></wbr>chloro-<wbr></wbr>4-<wbr></wbr>nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate. For example, CNP-<wbr></wbr>β-<wbr></wbr>D-<wbr></wbr>maltoheptaoside and CNP-α-<wbr></wbr>maltotrioside are chromogenic substrates for α-<wbr></wbr>amylase. 2-<wbr></wbr>Chloro-<wbr></wbr>4-<wbr></wbr>nitrophenyl-<wbr></wbr>α-<wbr></wbr>D-<wbr></wbr>glucopyranoside is a conjugate of CNP and α-<wbr></wbr>D-<wbr></wbr>glucose. The related conjugate between CNP and β-<wbr></wbr>D-<wbr></wbr>glucose, 2-<wbr></wbr>chloro-<wbr></wbr>4-<wbr></wbr>nitrophenyl β-<wbr></wbr>D-<wbr></wbr>glucopyranoside, is used as a chromogenic substrate for glycosyltransferases. This product is a chromogenic substrate for enzymes that target the linkage between CNP and α-<wbr></wbr>D-<wbr></wbr>glucose.