2-deoxy-2-fluoro L-Fucose

• CAT Number: R065469
• CAS Number: 70763-62-1
• Molecular Formula: C6H11FO4
• Molecular Weight: 166.15
• Purity: ≥95%
• Synonyms: 2,6-dideoxy-2-fluoro-L-galactose
• Storage: -20°C
• IUPAC Name: (3S,4R,5S,6S)-3-fluoro-6-methyloxane-2,4,5-triol
• InChI: InChI=1S/C6H11FO4/c1-2-4(8)5(9)3(7)6(10)11-2/h2-6,8-10H,1H3/t2-,3-,4+,5-,6?/m0/s1
• InChIKey: IRKXGKIPOMIQOD-ZZWDRFIYSA-N
• SMILES: C[C@@H]([C@H]([C@H]([C@@H](C=O)F)O)O)O

2-Deoxy-2-fluoro L-Fucose(CAT: R065469) is a fluorinated analog of L-fucose, a monosaccharide involved in various biological processes, including cell signaling, immune response, and glycosylation. The substitution of a fluorine atom at the 2-position makes this compound a valuable tool in biochemical research, particularly in studying the mechanisms of fucosylation and its role in disease states. This analog is often used in enzymatic studies to investigate the activity of fucosyltransferases and other glycosylation-related enzymes, as the fluorine substitution can inhibit or alter enzyme activity, providing insights into enzyme function and specificity. 2-Deoxy-2-fluoro L-Fucose is also of interest in developing potential therapeutic agents targeting aberrant glycosylation pathways in cancer and other diseases.

Reference

1.Becker, D.J., and Lowe, J.B. Fucose: biosynthesis and biological function in mammals. Glycobiology 13(7), 41R-53R (2003).