2’-Deoxy-2’-fluoroguanosine

• CAT Number: R020900
• CAS Number: 78842-13-4
• Molecular Formula: C10H12FN5O4
• Molecular Weight: 285.23
• Purity: ≥95%
• Synonyms: 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)guanine
• Target: Influenza Virus
• Storage: 2-8°C(protect from light)
• IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
• InChI: InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4-,6-,9-/m1/s1
• InChIKey: UXUZARPLRQRNNX-DXTOWSMRSA-N
• SMILES: C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N=C(NC2=O)N

2′-Deoxy-2′-fluoroguanosine（Cat No.:R020900）is a synthetic nucleoside analog of guanosine, where the hydrogen at the 2′-position of the sugar is replaced by a fluorine atom. This modification enhances the compound’s resistance to enzymatic degradation, making it a valuable tool in antiviral and anticancer research. It is particularly useful in the development of nucleotide-based inhibitors targeting viral replication and DNA synthesis. 2′-Deoxy-2′-fluoroguanosine has shown potential in the treatment of various cancers and viral infections, offering a stable and potent alternative to natural nucleosides in therapeutic applications.