2’-Deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]uridine

• CAT Number: R014381
• CAS Number: 115899-40-6
• Molecular Formula: C14H14F3N3O6
• Molecular Weight: 377.27
• Purity: ≥95%
• Synonyms: 3: PN: US20060183135 FIGURE: 7 claimed sequence; 2’-Deoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]uridine
• Storage: 2-8°C
• IUPAC Name: 2,2,2-trifluoro-N-[3-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynyl]acetamide
• InChI: InChI=1S/C14H14F3N3O6/c15-14(16,17)12(24)18-3-1-2-7-5-20(13(25)19-11(7)23)10-4-8(22)9(6-21)26-10/h5,8-10,21-22H,3-4,6H2,(H,18,24)(H,19,23,25)/t8-,9+,10+/m0/s1
• InChIKey: HCKMZBZCHQQZRJ-IVZWLZJFSA-N
• SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C#CCNC(=O)C(F)(F)F)CO)O

2’-Deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]uridine (Cat No.:R014381) is a synthetic nucleoside analog. It consists of a uridine base linked to a deoxyribose sugar, with a 3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl group at the 5’ position. This compound has potential applications in medicinal chemistry and molecular biology research due to its modified nucleoside structure. The trifluoroacetyl-amino-propynyl modification adds unique properties that may be useful in exploring novel therapeutics or probing specific interactions in nucleic acid-based systems, providing valuable insights in scientific investigations.