2’-Deoxy-5-azacytidylyl-(3’→5’)-2’-deoxy-guanosine Sodium Salt

• CAT Number: R041786
• CAS Number: 929904-85-8
• Molecular Formula: C18H23N9NaO10P
• Molecular Weight: 579.40
• Purity: ≥95%
• Target: DNA Methyltransferase
• Storage: +4 ℃
• IUPAC Name: sodium;[(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [(2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] phosphate
• InChI: InChI=1S/C18H24N9O10P.Na/c19-16-22-6-27(18(31)25-16)12-2-8(9(3-28)35-12)37-38(32,33)34-4-10-7(29)1-11(36-10)26-5-21-13-14(26)23-17(20)24-15(13)30;/h5-12,28-29H,1-4H2,(H,32,33)(H2,19,25,31)(H3,20,23,24,30);/q;+1/p-1/t7-,8-,9+,10+,11+,12+;/m0./s1
• InChIKey: XLHBNJPXFOZFNJ-BYKQGDNKSA-M
• SMILES: C1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)COP(=O)([O-])OC4CC(OC4CO)N5C=NC(=NC5=O)N)O.[Na+]

2’-Deoxy-5-azacytidylyl-(3’→5’)-2’-deoxy-guanosine Sodium Salt(CAT: R041786) is a synthetic oligonucleotide analog that contains the modified nucleoside 5-azacytidine. This compound is used in research to study DNA methylation and gene regulation, as 5-azacytidine can inhibit DNA methyltransferase enzymes, leading to hypomethylation of DNA. This inhibition affects gene expression and is useful for investigating epigenetic mechanisms, particularly in cancer research where abnormal methylation patterns are common. 2’-Deoxy-5-azacytidylyl-(3’→5’)-2’-deoxy-guanosine Sodium Salt is valuable for exploring therapeutic strategies aimed at reactivating tumor suppressor genes by reducing DNA methylation in oncogenic pathways.