2'-Deoxy-5-formylcytidine

• CAT Number: I044112
• CAS Number: 137017-45-9
• Molecular Formula: C10H13N3O5
• Molecular Weight: 255.23
• Purity: ≥95%
• Synonyms: 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidine-5-carbaldehyde
• InChI: InChI=1S/C10H13N3O5/c11-9-5(3-14)2-13(10(17)12-9)8-1-6(16)7(4-15)18-8/h2-3,6-8,15-16H,1,4H2,(H2,11,12,17)/t6-,7+,8+/m0/s1
• InChIKey: QBADNGFALQJSIH-XLPZGREQSA-N
• SMILES: C1C(C(OC1N2C=C(C(=NC2=O)N)C=O)CO)O

2′-Deoxy-5-formylcytidine is an effective internal triplet photosensitizer in DNA. 2′-Deoxy-5-formylcytidine could act as a new hot spot in DNA photodamage[1].

Reference

[1]. Wang X, et al. Ultrafast Intersystem Crossing in Epigenetic DNA Nucleoside 2′-Deoxy-5-formylcytidine. J Phys Chem B. 2019;123(27):5782-5790.
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