2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine 3’-CE Phosphoramidite

• CAT Number: R024241
• CAS Number: 93183-15-4
• Molecular Formula: C44H54N7O8P
• Molecular Weight: 839.93
• Purity: ≥95%
• Synonyms: 5’-O-[Bis(4-​methoxyphenyl)​phenylmethyl]​-2’-deoxy-N-(2-methyl-1-oxopropyl)​-guanosine 3’-[2-cyanoethyl N,​N-bis(1-methylethyl)​phosphoramidite]; 5’-O-[Bis(4-methoxyphenyl)phenylmethyl]-2’-deoxy-N-(2-methyl-1-oxopropyl)-guanosine 3’-[2-cyanoethyl bi
• Target: DNA/RNA Synthesis
• Storage: 2-8°C
• IUPAC Name: N-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
• InChI: InChI=1S/C44H54N7O8P/c1-28(2)41(52)48-43-47-40-39(42(53)49-43)46-27-50(40)38-25-36(59-60(57-24-12-23-45)51(29(3)4)30(5)6)37(58-38)26-56-44(31-13-10-9-11-14-31,32-15-19-34(54-7)20-16-32)33-17-21-35(55-8)22-18-33/h9-11,13-22,27-30,36-38H,12,24-26H2,1-8H3,(H2,47,48,49,52,53)/t36-,37+,38+,60?/m0/s1
• InChIKey: FDRMKYVTIFSDPR-MMROLVBFSA-N
• SMILES: CC(C)C(=O)NC1=NC(=O)C2=C(N1)N(C=N2)C3CC(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N

2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine 3’-CE Phosphoramidite (Cat No.:R024241) is a synthetic compound used in DNA synthesis. It contains a 2’-deoxyribose backbone with a dimethoxytrityl (DMT) protecting group at the 5’ position and an isobutyryl group at the N2 position of guanosine. The 3’-CE (3’-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite) modification facilitates attachment to growing DNA chains. This reagent is crucial in solid-phase oligonucleotide synthesis, enabling efficient and precise construction of oligonucleotides for various biotechnological and biomedical applications, including research, diagnostics, and therapeutics.