For research use only. Not for therapeutic Use.
2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1].
| Catalog Number | I044408 |
| CAS Number | 33068-19-8 |
| Synonyms | disodium;[(2R,3S,4R)-2,3,4-trihydroxy-6-oxohexyl] phosphate |
| Molecular Formula | C6H11Na2O8P |
| Purity | ≥95% |
| InChI | InChI=1S/C6H13O8P.2Na/c7-2-1-4(8)6(10)5(9)3-14-15(11,12)13;;/h2,4-6,8-10H,1,3H2,(H2,11,12,13);;/q;2*+1/p-2/t4-,5-,6+;;/m1../s1 |
| InChIKey | OKITYZJBWJMLMD-SYDFPMGNSA-L |
| SMILES | C(C=O)C(C(C(COP(=O)([O-])[O-])O)O)O.[Na+].[Na+] |
| Reference | [1]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30. [2]. B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234. |
