For research use only. Not for therapeutic Use.
2′-Deoxy-N1-methylguanosine(Cat No.:I041274)is a modified nucleoside where the guanine base is methylated at the N1 position, and the sugar is in its deoxyribose form. This modification alters the structure of DNA and may influence its stability, replication, and repair mechanisms. 2′-Deoxy-N1-methylguanosine is often used in research to study the effects of base modifications on DNA function, including mutagenesis and DNA damage repair. Its properties make it a valuable tool in understanding the role of methylation in gene expression and in exploring potential therapeutic applications, particularly in cancer and genetic disorders.
CAS Number | 5132-79-6 |
Synonyms | 2-amino-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one |
Molecular Formula | C11H15N5O4 |
Purity | ≥95% |
IUPAC Name | 2-amino-9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one |
InChI | InChI=1S/C11H15N5O4/c1-15-10(19)8-9(14-11(15)12)16(4-13-8)7-2-5(18)6(3-17)20-7/h4-7,17-18H,2-3H2,1H3,(H2,12,14) |
InChIKey | VJSHSPNFYFRXGN-UHFFFAOYSA-N |
SMILES | CN1C(=O)C2=C(N=C1N)N(C=N2)C3CC(C(O3)CO)O |