2’-Deoxy-N3-methylcytidine hydriodide

• CAT Number: I040901
• CAS Number: 79043-77-9
• Molecular Formula: C10H16IN3O4
• Molecular Weight: 369.16
• Purity: ≥95%
• Synonyms: 1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-imino-3-methylpyrimidin-2-one;hydroiodide
• InChI: InChI=1S/C10H15N3O4.HI/c1-12-8(11)2-3-13(10(12)16)9-4-6(15)7(5-14)17-9;/h2-3,6-7,9,11,14-15H,4-5H2,1H3;1H/t6-,7-,9-;/m1./s1
• InChIKey: DFGPJCYBYINQQK-JJVRHELESA-N
• SMILES: CN1C(=N)C=CN(C1=O)C2CC(C(O2)CO)O.I

2’-Deoxy-N3-methylcytidine hydriodide is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Reference

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
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