2’-Deoxy-N4-methylcytidine

• CAT Number: I041270
• CAS Number: 22882-02-6
• Molecular Formula: C10H15N3O4
• Molecular Weight: 241.24
• Purity: ≥95%
• Synonyms: 1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(methylamino)pyrimidin-2-one
• InChI: InChI=1S/C10H15N3O4/c1-11-8-2-3-13(10(16)12-8)9-4-6(15)7(5-14)17-9/h2-3,6-7,9,14-15H,4-5H2,1H3,(H,11,12,16)/t6-,7-,9-/m1/s1
• InChIKey: DNYQNXJGNKQOQK-ZXFLCMHBSA-N
• SMILES: CNC1=NC(=O)N(C=C1)C2CC(C(O2)CO)O

2’-Deoxy-N4-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Reference

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
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