For research use only. Not for therapeutic Use.
<span style="color:#000000;"><span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;">2’-Deoxyuridine (CAS 951-78-0) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2′-Deoxyuridines is used as labeling substrates include chloro-2′-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). </span></span></span>
| Catalog Number | R005821 |
| CAS Number | 951-78-0 |
| Synonyms | 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil;2’-Desoxyuridine;Deoxyribose Uracil; Deoxyuridine; NSC 23615; Uracil Deoxyriboside; |
| Molecular Formula | C9H12N2O5 |
| Purity | ≥95% |
| Target | Endogenous Metabolite |
| Storage | -20°C |
| IUPAC Name | 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| InChI | InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1 |
| InChIKey | MXHRCPNRJAMMIM-SHYZEUOFSA-N |
| SMILES | C1C(C(OC1N2C=CC(=O)NC2=O)CO)O |
| Reference | <span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">1.Wu, Shao-yu, et al. "Development of modified siRNA molecules incorporating 5-fluoro-2′-deoxyuridine residues to enhance cytotoxicity." <i style="font-family: Arial, sans-serif; font-size: 13px;">Nucleic acids research</i> 41.8 (2013): 4650-4659.<br /> |
