2-Desmethylbenzaldehyde Tolvaptan

• CAT Number: C000636
• CAS Number: 1432725-24-0
• Molecular Formula: C₁₈H₁₉ClN₂O₂
• Molecular Weight: 330.81
• Purity: ≥95%
• Synonyms: (4-Amino-2-methylphenyl)(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)methanone; 1-(2-Methyl-4-aminobenzoyl)-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Inert atmosphere
• IUPAC Name: (4-amino-2-methylphenyl)-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
• InChI: InChI=1S/C18H19ClN2O2/c1-11-9-13(20)5-6-14(11)18(23)21-8-2-3-17(22)15-10-12(19)4-7-16(15)21/h4-7,9-10,17,22H,2-3,8,20H2,1H3
• InChIKey: XVFPODYXXNMTEB-UHFFFAOYSA-N
• SMILES: CC1=C(C=CC(=C1)N)C(=O)N2CCCC(C3=C2C=CC(=C3)Cl)O

2-Desmethylbenzaldehyde Tolvaptan（Cat No.:C000636）, appears to be a chemical compound related to tolvaptan. Tolvaptan is a medication used to treat conditions of excess fluid retention, such as in patients with heart failure or liver cirrhosis. The presence of 2-Desmethylbenzaldehyde in the compound’s name suggests a structural modification, which can impact its pharmacological properties or synthesis.

Reference

Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006);