2-Fluoro-5-(trifluoromethyl)benzonitrile

• CAT Number: L047796
• CAS Number: 4088-84-0
• Molecular Formula: C8H3F4N
• Molecular Weight: 189.11
• Purity: ≥95%
• IUPAC Name: 2-fluoro-5-(trifluoromethyl)benzonitrile
• InChI: InChI=1S/C8H3F4N/c9-7-2-1-6(8(10,11)12)3-5(7)4-13/h1-3H
• InChIKey: LCLVMSCLLULGRY-UHFFFAOYSA-N

2-Fluoro-5-(trifluoromethyl)benzonitrile(CAT: L047796) is an aromatic compound featuring both a fluorine atom at the 2-position and a trifluoromethyl (CF₃) group at the 5-position on a benzonitrile ring. This structure makes it a valuable intermediate in organic synthesis, particularly for pharmaceuticals and agrochemicals. The trifluoromethyl group adds significant electron-withdrawing properties and lipophilicity, enhancing the compound’s stability and metabolic resistance, while the nitrile group can serve as a reactive site for further functionalization. In medicinal chemistry, such fluorinated benzonitriles are often used in the development of bioactive compounds, contributing to improved pharmacokinetic profiles, binding affinity, and selectivity for target receptors.