For research use only. Not for therapeutic Use.
2-Fluorobenzyl olaparib-d₄(CAT: I040839) is a deuterium-labeled analog of a 2-fluorobenzyl derivative of olaparib, a potent PARP (poly ADP-ribose polymerase) inhibitor used in cancer research. The incorporation of four deuterium atoms enhances its utility as an internal standard in LC-MS/MS assays for pharmacokinetic and metabolic studies. This compound is particularly valuable for accurately quantifying olaparib derivatives in biological samples, enabling precise monitoring in drug development, bioavailability, and therapeutic efficacy studies. 2-Fluorobenzyl olaparib-d₄ supports advanced research in oncology, especially in exploring DNA repair mechanisms and the treatment of BRCA-mutated cancers.
| CAS Number | 2732919-14-9 |
| Synonyms | 4-[[2-fluoro-3-[4-(2,2,3,3-tetradeuteriocyclopropanecarbonyl)piperazine-1-carbonyl]phenyl]methyl]-2H-phthalazin-1-one |
| Molecular Formula | C24H19D4FN4O3 |
| Purity | ≥95% |
| IUPAC Name | 4-[[2-fluoro-3-[4-(2,2,3,3-tetradeuteriocyclopropanecarbonyl)piperazine-1-carbonyl]phenyl]methyl]-2H-phthalazin-1-one |
| InChI | InChI=1S/C24H23FN4O3/c25-21-16(14-20-17-5-1-2-6-18(17)22(30)27-26-20)4-3-7-19(21)24(32)29-12-10-28(11-13-29)23(31)15-8-9-15/h1-7,15H,8-14H2,(H,27,30)/i8D2,9D2 |
| InChIKey | OXEZBBMVOZEGNT-LZMSFWOYSA-N |
| SMILES | [2H]C1(C(C1([2H])[2H])C(=O)N2CCN(CC2)C(=O)C3=CC=CC(=C3F)CC4=NNC(=O)C5=CC=CC=C54)[2H] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
