2’-hydroxy Cocaine

• CAT Number: R066701
• CAS Number: 89339-17-3
• Molecular Formula: C17H21NO5
• Molecular Weight: 319.43
• Purity: ≥95%
• Synonyms: Cocaine metabolite;o-hydroxy Cocaine;ortho-hydroxy Cocaine;Salicylmethylecgonine
• Storage: -20°C
• IUPAC Name: methyl (1R,2R,3S,5S)-3-(2-hydroxybenzoyl)oxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
• InChI: InChI=1S/C17H21NO5/c1-18-10-7-8-12(18)15(17(21)22-2)14(9-10)23-16(20)11-5-3-4-6-13(11)19/h3-6,10,12,14-15,19H,7-9H2,1-2H3/t10-,12+,14-,15+/m0/s1
• InChIKey: PEISRHQJLATJPJ-MMMKDXCPSA-N
• SMILES: CN1[C@H]2[C@@H](C(OC)=O)[C@@H](OC(C3=C(O)C=CC=C3)=O)C[C@@H]1CC2

2’-Hydroxy Cocaine(CAT: R066701) is a hydroxylated derivative of cocaine, a naturally occurring alkaloid found in the leaves of the Erythroxylum coca plant. This compound is structurally similar to cocaine but features a hydroxyl group at the 2’ position on the tropane ring. The addition of the hydroxyl group can alter the pharmacokinetic and pharmacodynamic properties of the molecule, potentially affecting its interaction with biological targets such as neurotransmitter transporters. 2’-Hydroxy Cocaine is studied for its effects on the central nervous system, including its potential as a tool in research focused on the mechanisms of addiction, dopamine uptake, and the development of therapeutics for substance abuse disorders. Its unique structure provides insights into the relationship between chemical modifications of cocaine and their biological activities.