For research use only. Not for therapeutic Use.
2-hydroxy Lignoceric acid is an α-hydroxy very long chain fatty acid that is normally present in the mammalian nervous system. In the brain, 2-hydroxy lignoceric acid is derived from lignoceric acid (Item No. <span class=/itemid/>13353</span>) and further converted to ceramides and cerebrosides during the process of nerve sheath myelination. 2-hydroxy Lignoceric acid is produced by the α-oxidation of lignoceric acid in the peroxisome and defects in this pathway are associated with disorders such as Zellweger syndrome.
| Catalog Number | R067187 |
| CAS Number | 544-57-0 |
| Synonyms | Cerebronic Acid |
| Molecular Formula | C24H48O3 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 2-hydroxytetracosanoic acid |
| InChI | InChI=1S/C24H48O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23(25)24(26)27/h23,25H,2-22H2,1H3,(H,26,27) |
| InChIKey | MSUOLNSQHLHDAS-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCCCCCCCCC(C(=O)O)O |
| Reference | 1.Hoshi, M. and Kishimoto, Y. Synthesis of cerebronic acid from lignoceric acid by rat brain preparation. Some properties and distribution of the α-hydroxylation system. J. Biol. Chem. 248(11), 4123-4130 (1973). |
