2-Methylbutyrylcarnitine

• CAT Number: I041326
• CAS Number: 256928-75-3
• Molecular Formula: C12H23NO4
• Molecular Weight: 245.32
• Purity: ≥95%
• Synonyms: (3R)-3-(2-methylbutanoyloxy)-4-(trimethylazaniumyl)butanoate
• InChI: InChI=1S/C12H23NO4/c1-6-9(2)12(16)17-10(7-11(14)15)8-13(3,4)5/h9-10H,6-8H2,1-5H3/t9?,10-/m1/s1
• InChIKey: IHCPDBBYTYJYIL-QVDQXJPCSA-N
• SMILES: CCC(C)C(=O)OC(CC(=O)[O-])C[N+](C)(C)C

2-Methylbutyrylcarnitine is a fatty acid metabolite. 2-Methylbutyrylcarnitine is found mainly in the blood and urine of humans and animals and is produced through the pyruvate carboxylation pathway. 2-Methylbutyrylcarnitine exhibits high level in the plasma of subjects with steatohepatitis (NASH) and can be used as an indicator for the diagnosis of metabolic diseases[1].

Reference

[1]. Kalhan SC, et al. Plasma metabolomic profile in nonalcoholic fatty liver disease. Metabolism. 2011 Mar;60(3):404-13.
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