2-Methylthioadenosine diphosphate trisodium salt

• CAT Number: I010433
• CAS Number: 475193-31-8
• Molecular Formula: C11H14N5O10P2S • 3Na
• Molecular Weight: 539.20
• Purity: ≥95%
• Synonyms: Alternative Names: 2-(Methylthio)adenosine 5/’-diphosphate, 2-Methylthio-ADP, MeSADP
• Target: P2Y Receptor
• Solubility: Soluble in water (supplied pre-dissolved at a concentration of 10mM)
• Storage: Store at -20C
• IUPAC Name: trisodium;[[(2R,3S,4R,5R)-5-(6-amino-2-methylsulfanylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate
• InChI: InChI=1S/C11H17N5O10P2S.3Na/c1-29-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(25-10)2-24-28(22,23)26-27(19,20)21;;;/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,23)(H2,12,14,15)(H2,19,20,21);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1
• InChIKey: DYNGCIHMNWOBSU-MSQVLRTGSA-K
• SMILES: CSC1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])[O-])O)O)N.[Na+].[Na+].[Na+]

2-Methylthioadenosine diphosphate trisodium salt (Cat No.:I010433) is a nucleotide analog that plays a role in biochemical processes involving adenosine metabolism. It is often used in research to study purine metabolism and cellular signaling pathways. The compound acts as a substrate for enzymes involved in methylation reactions and may inhibit certain enzymes in the purine salvage pathway. Its applications extend to understanding cell growth regulation, cancer research, and studies on immune cell activation. While not a widely used therapeutic agent, 2-MTADP serves as a valuable tool in molecular and cellular biology research.