2-MPPA

• CAT Number: R063630
• CAS Number: 254737-29-6
• Molecular Formula: C8H14O4S
• Molecular Weight: 206.256
• Purity: ≥95%
• Synonyms: 2-(3-Mercaptopropyl)pentanedioic Acid; 2-(3-Sulfanylpropyl)pentanedioic acid; GPI 5693
• Target: Carboxypeptidase
• Solubility: Soluble in DMSO > 10 mM
• Storage: Store at -20 ℃
• IUPAC Name: 2-(3-sulfanylpropyl)pentanedioic acid
• InChI: InChI=1S/C8H14O4S/c9-7(10)4-3-6(8(11)12)2-1-5-13/h6,13H,1-5H2,(H,9,10)(H,11,12)
• InChIKey: FNLNSQHJKVQCBP-UHFFFAOYSA-N
• SMILES: C(CC(CCC(=O)O)C(=O)O)CS

2-MPPA is a potent and selective antagonist of the group II metabotropic glutamate receptor (mGluR), known for its role in modulating glutamate transmission. By inhibiting these receptors, 2-MPPA has been shown to affect neuropsychiatric conditions, including anxiety, depression, and schizophrenia. Its unique mechanism of action makes it a valuable tool for studying the role of mGluR in neurological disorders and developing potential therapeutic interventions targeting glutamatergic pathways in the brain.