For research use only. Not for therapeutic Use.
2-NP is a selective enhancer of STAT1 transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells[1].
Catalog Number | I043948 |
CAS Number | 65182-56-1 |
Synonyms | 2-(1,8-naphthyridin-2-yl)phenol |
Molecular Formula | C14H10N2O |
Purity | ≥95% |
InChI | InChI=1S/C14H10N2O/c17-13-6-2-1-5-11(13)12-8-7-10-4-3-9-15-14(10)16-12/h1-9,17H |
InChIKey | AYKMXKNVEUMLFQ-UHFFFAOYSA-N |
SMILES | C1=CC=C(C(=C1)C2=NC3=C(C=CC=N3)C=C2)O |
Reference | [1]. Lynch RA, et, al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61. |