For research use only. Not for therapeutic Use.
2′-O-MOE-5-Me-rC（Cat No.:I043010）, also known as 5-methyl-2′-O-(2-methoxyethyl)cytidine, is a modified nucleoside derivative commonly used in oligonucleotide synthesis. This compound features a 2′-O-(2-methoxyethyl) modification on the ribose sugar and a methyl group at the 5-position of the cytosine base. These modifications enhance the stability and binding affinity of oligonucleotides, making them valuable in therapeutic applications such as antisense oligonucleotides and small interfering RNAs (siRNAs). The molecular formula of 2′-O-MOE-5-Me-rC is C₁₃H₂₁N₃O₆, with a molecular weight of 315.32 g/mol. It appears as a white to off-white solid and should be stored at 2-8 °C, protected from light, to maintain its stability.
| CAS Number | 244105-55-3 |
| Synonyms | 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one |
| Molecular Formula | C13H21N3O6 |
| Purity | ≥95% |
| IUPAC Name | 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one |
| InChI | InChI=1S/C13H21N3O6/c1-7-5-16(13(19)15-11(7)14)12-10(21-4-3-20-2)9(18)8(6-17)22-12/h5,8-10,12,17-18H,3-4,6H2,1-2H3,(H2,14,15,19)/t8-,9-,10-,12-/m1/s1 |
| InChIKey | GUEIFVRYWPOXHJ-DNRKLUKYSA-N |
| SMILES | CC1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)OCCOC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
