For research use only. Not for therapeutic Use.
2’-O-Succinyl-cAMP (2’-O-succinyladenosine 3’,5’-cyclic monophosphate) (Cat.No: I020846) is a derivative of cAMP that is widely used as a research tool to study the role of cyclic nucleotides in various biological processes. It can be used to activate protein kinase A (PKA) and to stimulate the production of cAMP response element-binding protein (CREB). It is also a substrate for phosphodiesterase enzymes.
| Catalog Number | I020846 |
| CAS Number | 36940-87-1 |
| Synonyms | 2’-O-Succinyl-cAMP; 2’-O-Succinyl-3’,5’-cyclic AMP |
| Molecular Formula | C14H16N5O9P |
| Purity | 98% |
| Target | Cholinesterase (ChE) |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| IUPAC Name | 4-(((4aR,6R,7R,7aR)-6-(6-amino-9H-purin-9-yl)-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl)oxy)-4-oxobutanoic acid |
| InChI | InChI=1S/C14H16N5O9P/c15-12-9-13(17-4-16-12)19(5-18-9)14-11(27-8(22)2-1-7(20)21)10-6(26-14)3-25-29(23,24)28-10/h4-6,10-11,14H,1-3H2,(H,20,21)(H,23,24)(H2,15,16,17)/t6-,10-,11-,14-/m1/s1 |
| InChIKey | QNPSLGPIZRJDAN-UISLRAPISA-N |
| SMILES | NC1=C2C(N([C@]3([H])O[C@@](COP(O4)(O)=O)([H])[C@]4([H])[C@H]3OC(CCC(O)=O)=O)C=N2)=NC=N1 |
| Reference | 1: Ezan, E., Mamas, S., Rougeot, C., et al. Strategies for developing specific and sensitive hapten radioimmunoassays. Radioimmunoassay in Basic and Clinical Pharmacology 143-179 (1987). |
