2'-O,4'-C-Methyleneadenosine

• CAT Number: I030931
• CAS Number: 206055-70-1
• Molecular Formula: C11H13N5O4
• Molecular Weight: 279.25
• Purity: ≥95%
• Synonyms: (1S,3R,4S)-3-(6-aminopurin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol
• IUPAC Name: (1S,3R,4R,7S)-3-(6-aminopurin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol
• InChI: InChI=1S/C11H13N5O4/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(18)11(1-17,20-10)2-19-6/h3-4,6-7,10,17-18H,1-2H2,(H2,12,13,14)/t6-,7+,10-,11+/m1/s1
• InChIKey: GHKDRNDFVCEETA-KYAGDKKUSA-N
• SMILES: C1[C@]2([C@H]([C@@H](O1)[C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)CO

2′-O,4′-C-Methyleneadenosine（Cat No.:I030931）is a modified adenosine analog in which the oxygen at the 2′ position and the carbon at the 4′ position of the ribose ring are replaced with a methylene group. This structural modification increases the stability of the molecule by protecting it from enzymatic degradation, particularly from ribonucleases. The compound can be used in RNA research to study adenosine-related processes, including RNA folding and interaction. It holds potential for therapeutic applications in antiviral, anticancer, and genetic therapies, where enhanced stability and controlled activity of RNA molecules are crucial.