2'-O,4'-C-Methyleneadenosine

For research use only. Not for therapeutic Use.

  • CAT Number: I030931
  • CAS Number: 206055-70-1
  • Molecular Formula: C11H13N5O4
  • Molecular Weight: 279.25
  • Purity: ≥95%
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2′-O,4′-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1].


Catalog Number I030931
CAS Number 206055-70-1
Synonyms

(1S,3R,4S)-3-(6-aminopurin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol

Molecular Formula C11H13N5O4
Purity ≥95%
InChI InChI=1S/C11H13N5O4/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(18)11(1-17,20-10)2-19-6/h3-4,6-7,10,17-18H,1-2H2,(H2,12,13,14)/t6-,7?,10+,11-/m0/s1
InChIKey GHKDRNDFVCEETA-LYFOIYRLSA-N
SMILES C1C2(C(C(O1)C(O2)N3C=NC4=C(N=CN=C43)N)O)CO
Reference

[1]. Ravn J, et al. Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem. 2007 Aug 15;15(16):5440-7.
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